Author/Authors :
hassikou, hasna hôpital militaire moulay ismail - service de rhumatologie, Meknès, Morocco , youssoufi, tarik hôpital militaire moulay ismail - service de rhumatologie, Meknès, Morocco , essouiri, jamila hôpital militaire moulay ismail - service de rhumatologie, Meknès, Morocco , haddani, fatima zahra hôpital militaire moulay ismail - service de rhumatologie, Meknès, Morocco , el bennaye, jalal hôpital militaire moulay ismail - service de dermatologie, Meknès, Morocco , tabache, fatima hôpital militaire moulay ismail - service de rhumatologie, Meknès, Morocco
Abstract :
Amyloidosis is unusual disease that canaffect many organs in a highly variable way.It is characterized by an accumulation oftissue deposits of proteins able to adopt anabnormal fibrillar conformation (called amyloidsubstance) and of which the β-pleated structureis resistant to proteolysis.We distinguish amyloidosis AL (primitive)isolated or associated with myeloma, ofwhich often belongs amyloid lichen andamyloidosis AA (secondary or reactive), withan infection, chronic inflammation, tumors...The combination of the secondary form torheumatoid arthritis remains the most common.However, the association of rheumatoidarthritis to cutaneous lichen has rarely beendescribed in the literature.We report the observation of a 61 years old manfollowed for 20 years for rheumatoid arthritisthat is deforming and destructive. He has beenpresent for 2 years an erythemato-papulo squamous plates spread on the anterior face ofthe 2 legs. The cutaneous biopsy was in favourof an amyloid lichen. The extensive assessmentdid not find any systemic impairment.
