Barutcuoğlu, Burcu Ege University - Faculty of Medicine - Department of Biochemistry, Turkey , Bozdemir, Erkin Ege University - Faculty of Medicine - Department of Biochemistry, Turkey , Başol, Güneş Ege University - Faculty of Medicine - Department of Biochemistry, Turkey , Bayındır, Oya Ege University - Faculty of Medicine - Department of Biochemistry, Turkey

Is percent free prostate specific antigen test used more than recommended by international standarts for prostate cancer screening?

32943

Aim. For prostate cancer (PCa) screening “percent free prostate specific antigen” (pfPSA) testing is used for improving test specificity of prostate specific antigen (tPSA) and is used when tPSA is between 2.5 and 10 ng/mL, according to international screening guidelines of American Urological Association (AUA), and American Cancer Society (ACS). We evaluated the number of pfPSA testing requested in practice and the concordance to PCa screening guidelines. Method. The number of pfPSA testing performed at different age groups and different tPSA levels had evaluated, in our hospital between 2004 and 2007. Result. Twenty five thousand eight hundred and forty five pfPSA tests were performed between 2004 and 2007. Only 23.7 % of men were at tPSA levels 2.5-10 ng/mL. 9.8 % of patients were under age 45 years, and 10.2 % of them were over 75 years. Conclusion. There is no real pfPSA screening consistency with screening guidelines. Laboratories, clinicians and practitioners should overview their pfPSA requests for PCa screening.

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Prostate cancer screening , Prostate specific antigen , percent free prostate specific antigen

Cumhuriyet Medical Journal

163