Yüksel, Fadime Adalet Bakanlığı Adli Tıp Kurumu - Çocuk Sağlığı ve Hastalıkları Kliniği, Turkey , Büyükkayhan, Derya Haseki Eğitim ve Araştırma Hastanesi - Çocuk Sağlığı ve Hastalıkları Kliniği, Turkey , Kara, Semra Fatih Üniversitesi Tıp Fakültesi Hastanesi TR- 06510 - Çocuk Sağlığı ve Hastalıkları Neonatoloji Bilim Dalı, Turkey , Cevit, Ömer Cumhuriyet Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları Allerji ve İmmünoloji Bilim Dalı, Turkey , Çetin, Ali Cumhuriyet Üniversitesi - Tıp Fakültesi - Kadın Hastalıkları ve Doğum Anabilim Dalı, Turkey , Kaya, Ali Cumhuriyet Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Turkey

The lipid profile of the cord blood can determine the risk of the atheroscleotic cardiovascular disease ?

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Aim. Hypercholesterolemia is the most important causes of atherosclerosis. Serum lipid abnormalities begin in childhood and that atherosclerotic lesions emerge early in life. In this study, the lipid profiles of the cord blood in newborns were compared in terms of gestational parameters, maternal parameters, maternal lipid profiles .Method. Plasma total cholesterol, triglycerides, high density lipoprotein (HDL), low density lipoprotein and very low density lipoprotein were measured in the cord blood of newborns and in serum of the mothers. The relations between cord plasma lipids values and clinical findings of newborns and their mothers were investigated. Results. Cord blood lipid levels were lower than those in adults. Cord blood HDL levels were correlated positively with maternal HDL levels (r= 0.419, p=0.03). However, there were no significant relations between the triglycerides-cholesterol and other lipoproteins levels in cord and maternal blood (p 0.05). Conclusion. We suggest that cord blood HDL levels have a predictive value in the development of the atherosclerosis in later stages of life.

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Atherosclerosis , lipid levels , high density lipoprotein , cord blood , newborn

Cumhuriyet Medical Journal

171