Author/Authors :
Çetin, Meral Cumhuriyet University - School of Medicine - Department of Obstetrics and Gynecology, Turkey , Yıldız, Çağlar Cumhuriyet Üniversitesi - School of Medicine - Department of Obstetrics and Gynecology, Turkey
Abstract :
Aim. The aim of this study was to determine the efficacy of oral and vaginal misoprostol administered for cervical priming in nullipar women before first-trimester surgical abortion. Methods. Medical records of 84 nulliparous women, aged 18-42 years, who admitted for pregnancy termination request were reviewed retrospectively. The pregnancies were between 5 and 10 weeks of gestation. 100 μg misoprostol was administered by oral and vaginal route in 84 patients. The doses repeated 4 hours later. Exclusion criteria were systemic disease, a history of cervical operations, bleeding or spotting during the current pregnancy and basal cervical dilation greater than 4mm. Results. Targeted cervical dilatation for pregnancy termination was determined according to gestational age of every patient (for gestations at 5, 6, 7, 8, 9, and 10 weeks, required cervical dilatations from 5, 6, 7, 8, 9, and 10 mm, respectively). A significant correlation was found between gestational ages and achieved cervical dilatation after misoprostol use. Conclusions. Suggested administration of misoprostol provides adequate cervical dilatation. Use of cervical dilators is not necessary during curettage after administration 100 μg misoprostol oral and vaginal two times four hours apart from five to ten weeks of pregnancy.
