Karakülah, Mehmet Mersin State Hospital - Department of Plastic and Reconstructive Surgery, Turkey , Gümüş, Nazım Cumhuriyet University - School of Medicine - Plastik Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı, Turkey , Yılmaz, Sarper Cumhuriyet University - School of Medicine - Department of Plastic and Reconstructive Surgery, Turkey , Taylan, Gaye Kartal Lütfi Kırdar Teaching and Research Hospital, Turkey , Sezer, Hafize Cumhuriyet University - School of Medicine - Department of Plastic and Reconstructive Surgery, Turkey , Çelik, Uğur Recep Tokat State Hospital, Turkey

Serum immunoglobulin levels in the course of post-burn hypertrophic scar development with specific reference to immunoglobulin E

33091

Aim. The relation between the occurrence of the hypertrophic scar and serum immunoglobulin levels with specific reference to IgE was investigated in burn patients. Methods. This study included 20 burn patients hospitalized in our clinic. Serum levels of immunoglobulin A, G, M and E were measured in the first 48 hours, on the 10th day and on the 90th day during the treatment. Evaluation of the hypertrophic scar was made using Vankouver scar scale. The relation between the hypertrophic scar and serum levels of each immunoglobulins were analyzed. Results. Serum levels of immunoglobulin A, G and M decreased in the early postburn period, and they returned to normal in the following period. There were serious variations in the levels of IgE. In some patients the levels stayed within normal ranges, in some of them increased and in some of them decreased. Conclusion. There were no relation among the hypertrophic scar formation and levels of immunoglobulins A, G and M. We were unable to find a significant relation between the IgE levels and formation of hypertrophic scars; however, there were some peculiarities which we discussed.

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Burn , immunoglobulin , immunoglobulin E , hypertrophic scar

Cumhuriyet Medical Journal

464