مرکز منطقه ای اطلاع رساني علوم و فناوري - A preliminary study on ferrous metabolism and cortisol in psoriasis vulgaris

Abstract :

Aim. Psoriasis is a disease of the skin and joints, which is chronic, recurrent, and inflammatory. Although etiopathogenesis is a disease on which one of the most studied was made so far, it wasn’t gain a complete clearness. Experimental studies made about Psoriasis for the last 20 years, draws attention to coexistence psychology, neuroendocrinology, and of immunology in the etiology of the disease. The purpose of this study,is to emerge the relationship between ferrous metabolism, Creactive protein (CRP), cortisol values in patients with psoriasis vulgaris. Method. 12 women and 16 men who were diagnosed with psoriasis vulgaris were included in a total of 28 patients who were diagnosed with psoriasis vulgaris were included in the study. Age of patients, gender, and duration of disease were recorded. The patients serum ferrous, total iron binding capacity (TIBC), ferritin, CRP, whole blood and basal cortisol levels were measured. Results. It was observed that a strong correlation between Patients with ferrous values, CRP levels, and a moderate correlation between cortisol levels and TIBC values. Conclusions. Ferrous metabolism in patients with Psoriasis vulgaris should not be ignored. Especially the improvement of methods such as parenteral ferrous application which can apply to the period of inflammatory will make easy to control illness