Author/Authors :
Altınbaş, Akif Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Yılmaz, Barış Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Ekiz, Fuat Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Aktaş, Bora Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Çoban, Şahin Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Başar, Ömer Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Yüksel, Osman Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey
Abstract :
Aim. Delta hepatitis virus (HDV) needs the presence of HBsAg to cause disease. The success of the treatment of HDV infection is low even with interferon (IFN) based medications. Although the rates of HDV infection declines from east to west in our country, it was reported as 4% in inactive HBV carriers, 4.8-27.1% in chronic HBV infections, 20-46.3% in cirrhosis. Method. HBsAg positive patients admitted to Dıskapı Yıldırım Beyazıt Education and Research Hospital, Hepatology outpatient clinic between April 2009 and February 2011 were included in the study, retrospectively. Data of the patients were collected from the patients’ folder and the hospital’s digital archive. Results. In our study, approximately 80% of 348 patients were healthy HBV carriers or patients with chronic active HBV infection. Totally, seven (2%) patients were found to be positive for HDV antibodies. Two of them were also positive for HDV RNA in serum, one became negative in years without any specific medication, and the other three represented false negative results after repeated antibody tests. Conclusion. The rates of HDV infection among HBsAg positive patients was low in our region.
