Yücel, Birsen Cumhuriyet University - School of Medicine - Departments of Radiation Oncology, Turkey , Kılıçkap, Saadettin Cumhuriyet University - School of Medicine - Department of Radiation Oncology, Turkey , Okur, Yıllar Lehimcioğlu Cumhuriyet University - School of Medicine - Department of Radiation Oncology, Turkey , Erdiş, Eda Antakya State Hospital - Department of Radiation Oncology, Turkey , Akkaş, Ebru Atasever Cumhuriyet University - School of Medicine - Department of Radiation Oncology, Turkey , Şalk, Mine Urfa State Hospital - Department of Radiation Oncology, Turkey

Prognostic factors that affect the survival of gastric cancer

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Aims. The purpose of this study is to review the factors that affect the survival and clinicopathological characteristics of gastric cancer cases monitored and treated at our centre. Method. 112 gastric cancer patients who admitted to the Radiation Oncology Department of Cumhuriyet University Medical Faculty Research and Application Hospital between 2006 and 2010 were included in the study. The demographic, clinical, and histopathology data of the patients were obtained from the patient files and the hospital records. Results. This study analysed data of 112 patients of whom 90 (80%) were men, and 22 (20%) were women. The factors that determined survival were stage of the cancer, T and N stages, high grade, performance status, presence of anemia and hypoalbuminemia, presence of metastasis, extravascular invasion, weight loss, metastatic lymph node ratio ( 50%) and a high level of serum CEA and CA19-9. The stage, performance status, anemia at the time of diagnosis were determined as independent prognostic factors that affect survival after performing multivariate analysis. Conclusion. Many studies have defined numerous prognostic factors for gastric cancer. In concordance with the literature, this study sets forth that the most important factors in terms of prognosis are the stage, the performance status, and the presence of anemia at diagnosis the time of diagnosis.

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Gastric cancer , prognosis , anemia , stage , performance status

Cumhuriyet Medical Journal

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