Author/Authors :
ÇUBUK, Gülce Afyon Kocatepe Üniversitesi - Veteriner Fakültesi - Farmakoloji ve Toksikoloji Anabilim Dalı, Turkey , İNCE, Sinan Afyon Kocatepe Üniversitesi - Veteriner Fakültesi - Farmakoloji ve Toksikoloji Anabilim Dalı, Turkey
Abstract :
Diabetes mellitus is a chronic hyperglycemia metabolism disorder that leads to carbohydrate, protein, and fat metabolism disorders as a result of the effect of absolute or relative lack of insulin hormone secretion or insulin. Social point of view, due to the acute and chronic complications that can lead to disability and death, which reduces the quality of life and social-economic burden of a disease, is noteworthy. Patients with diabetes are forced to sustain a scheduled care throughout their life and get help from time to time. The treatment of diabetes, in 20 beginning of the century while the discovery of insulin was a turning point, the increase of information on the pathogenesis of the disease and advances in technology and the provision of control and tried to reach the targets for the prevention of complications. Antidiabetic drugs used to provide glucose control, but it is known to be limited in effect to stop the progression of the disease. In recent years, many new drugs developed for the treatment of diabetes, passing combination therapy achieved important goals.