Kader, Çiğdem Bozok University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey , Yolcu, Sadiye Bozok University - School of Medicine - Department of Emergency Medicine, Turkey , Erbay, Ayşe Bozok University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey

Evaluation of mean platelet volume (MPV) levels in brucellosis patients

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Aim. Brucellosis is a multisystemic infectious disease. An inflammatory process occurs in brucellosis which causes increase in acute phase reactants. Mean platelet volume (MPV) has been shown as an inflammatory marker in some diseases. In this study we searched the MPV levels of brucellosis patients. Method. MPV levels of forty-seven patients with brucellosis were evaluated. Results. We included a total of 47 brucellosis patients having an average age of 47.4±14.6 and sex distribution of 21 (44,7%) male and 26 (55,3%) female and also 47 control healthy subjects having an average age of 45,2±12,3 and sex distribution of 25 (53,2%) male and 22 (46,8%) female). Erythrocte sedimentation rate (ESR), MPV, red cell distribution width (RDW), Hemoglobin (Hgb) and white blood cell(WBC) values in pre-treatment stage were statistically different from after treatment period. MPV levels were significantly lower in the pretreatment group. Similarly RDW values were lower in pretreatment group. MPV levels of patients were not diffrent in the acute and subacute stage. There was not any significant difference in the MPV levels of patients with hepatomegaly and without hepatomegaly (MPV levels of patients with splenomegaly were lower than patients without splenomegaly Spearman’s correlation analysis showed a significant negative correlation between STAT (serum tube agglutination test) and MPV values. Conclusion. MPV levels may be useful in the follow-up of brucellosis patients.

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Brucellosis , acute phase reactant , mean platelet volume

Cumhuriyet Medical Journal

494