Author/Authors :
Arı, Semra Medeniyet University - School of Medicine, Göztepe Education and Research Hospital - Department of Neurology, Turkey , Candan, Fatma Medeniyet University - School of Medicine, Göztepe Education and Research Hospital - Department of Neurology, Turkey , Işık, Nihal Medeniyet University - School of Medicine, Göztepe Education and Research Hospital - Department of Neurology, Turkey , Öztop, Özgür Medeniyet University - School of Medicine, Göztepe Education and Research Hospital - Department of Neurology, Turkey , Cantürk, İlknur Aydın Medeniyet University - School of Medicine, Göztepe Education and Research Hospital - Department of Neurology, Turkey , Düz, Özge Arıcı Medeniyet University - School of Medicine, Göztepe Education and Research Hospital - Department of Neurology, Turkey
Abstract :
Aim. Autonomic symptoms (AS) are one of the major causes affecting quality of life in Parkinson’s disease (PD) patients and contribute to the disease burden. Our aim is to investigate the occurence of AS and to evaluate the relation between AS and the demographic and clinical features of PD patients. Method. In this study 66 idiopathic PD patients (47 men) were evaluated for the presence of AS during the last month with the SCOPA-AUT (Scales for Outcomes in Parkinson’s Disease; SCOPA) questionnaire, which consists of 23 items in six domains: gastrointestinal (7), urinary (6), cardiovascular (3), thermoregulatory (4), pupillomotor (1), and sexual (2). The maximum score is 69, with a score range per item from 0 (never experiencing the symptom) to 3 (often experiencing the symptom). Associations between AS and duration of disease, age onset of disease, treatment and Hoehn Yahr stage scores were also studied. Results. The mean (SD) age was 67.1 (9.5), disease duration 5.1 (3.9), age onset of disease 59 (10.9) years and Hoehn Yahr median stage 1.9 (0.75, range I-IV). The presence of AS in all patients was observed. Mean SCOPA-AUT score was 15.6 (4-32). Total SCOPA-AUT scores were found significantly associated with duration of disease and Hoehn Yahr stages (p 0.05), in contrast to age and gender. The most leading AS were in the gastorintestinal domain which was associated with the disease severity and duration also (p 0.05). Conclusion. AS were present in all patients even at the disease onset and early stages and increased with the disease severity and duration. For a better quality of life of the patient, it’ s important to evaluate the presence of AS and initiate the appropriate treatment.
NaturalLanguageKeyword :
Parkinson’s Disease , SCOPA , AUT , otonomıc symptoms
