Acıbucu, Fettah Sivas Numune Hospital - Department of Endocrinology, Turkey , Timuçin, Meryem Cumhuriyet University - Medical School - Departments of Nefrology, Turkey , Acıbucu, Duygu Oğuz Cumhuriyet University - Medical School - Departments of Biochemistry, Turkey

Insulin autoimmune syndrome associated with the use of thiocolchicoside: A Case report

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Insulin autoimmune syndrome (IAS) is a disease characterized by hypoglycemia and insulinantibodies without insulin usage. We report the case of a patient diagnosed with IAS that wasassociated with the use of thiocolchicoside. A 62-year-old female patient was admitted to ourclinic with fasting and postprandial hypoglycemia symptoms. She had a fasting glucose level of47mg/dl, and high insulin, C-peptide and insulin antibody levels were detected. However, she hadno signs of hypoglycemia during a 72 hour fasting test. In addition, the patient had usedthiocolchicoside for a week a month prior to the beginning of her symptoms, but she was nottaking any insulin or diabetic medications. A diagnosis of IAS was made, and the patient was puton an appropriate diet. Three months following this diagnosis, the patient’s comp laints haveminimilized, and the insulin and C-peptide levels have decreased.

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Insulin autoimmune syndrome , hypoglycemia , thiocolchicoside

Cumhuriyet Medical Journal

66