Beton, Osman Cumhuriyet University - Faculty of Medicine - Department of Cardiology, Turkey , Kurt, Recep Cumhuriyet University - Faculty of Medicine - Department of Cardiology, Turkey , Güneş, Hakan Sivas Numune Hospital - Cardiology Clinic, Turkey , Kaya, Hakkı Cumhuriyet University - Faculty of Medicine - Department of Cardiology, Turkey , Yılmaz, Mehmet Birhan Cumhuriyet University - Faculty of Medicine - Department of Cardiology, Turkey

Acute myocarditis induced by dosage increment of methylphenidate in an adolescent patient

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Attention deficit-hyperactivity disorder (ADHD) is one of the most common psychiatric disorders seen in children and adolescents. ADHD is increasingly diagnosed and treated nowadays. Methylphenidate is a potent psychostimulant that exerts its effects by increasing dopamine and norepinephrine levels in synapses. It is a widely used medication for treatment of ADHD in children and adolescents. Although not well-established, a causal relationship between treatment of ADHD and development of cardiomyopathy has been suggested. However, this suggestion was supported by the normalization or improvement in cardiac function and functional class after cessation of anti-ADHD medications in patients suffering from cardiomyopathy related to anti-ADHD medications. In this case report, we describe a case of 14-year-old male patient who developed acute myocarditis due to the dose increment of methylphenidate. The patient completely recovered after discontinuation of methylphenidate. Cardiovascular monitoring of patients on methylphenidate treatment should be an important task for psychiatrists, general practitioners and cardiologists.

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Attention deficit , hyperactivity disorder , methylphenidate , acute myocarditis

Cumhuriyet Medical Journal

152