SERDAR, Zehra Aşiran Haydarpaşa Numune Training and Research Hospital - Dermatology, Turkey , GÖNENÇ, Işık Haydarpaşa Numune Training and Research Hospital - Family Medicine, Turkey , YAŞAR, Şirin Haydarpaşa Numune Training and Research Hospital - Dermatology, Turkey , DORUK, Tuğba Haydarpaşa Numune Training and Research Hospital - Dermatology, Turkey , DÖNER, Nurhan Haydarpaşa Numune Training and Research Hospital - Dermatology, Turkey

Hand-Foot Syndrome Accompanied by Severe Oral Lesions during Capecitabine Therapy for Metastatic Colon Carcinoma

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Hand-foot syndrome (HFS) is a side effect of some chemotherapeutics appearing as dysesthesia, sharp-edged plaques and symmetrical lesions on palmoplantar areas. Our case is a 68-year-old male patient who developed a slight erythema and desquamation on the palms and soles of the feet during the third cycle of capecitabine treatment for advanced metastatic carcinoma. With this case report we aimed to draw attention to the development of HFS in patients receiving chemotherapy with capecitabine and raise awareness in the issue. The nonexistance of data in contemporary literature about the occurrence of hemorrhagic bullae in the oral mucosa makes our case noteworthy.

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Chemotherapy , induced , Palmoplantar erythema , Side effect , Chemotherapeutics , Drug , induced reaction , Capecitabine

Marmara Medical Journal

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