Author/Authors :
TÜKENMEZ TİGEN, Elif Marmara University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey , ERGÖNÜL, Önder Koc University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey , ALTINKANAT, Gülşen Marmara University - School of Medicine - Department of Microbiology, Turkey , ÖZGEN, Mahir Marmara Univesity - School of Medicine - Department of Urology, Turkey , ERTÜRK ŞENGEL, Buket Marmara University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey , ODABAŞI, Zekaver Marmara University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey , TÜRKERİ, Levent Marmara Univesity - School of Medicine - Department of Urology, Turkey , MÜLAZIMOĞLU, Lütfiye Marmara University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey , KORTEN, Volkan Marmara University - School of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey
Title Of Article :
Impact of fecal carriage of extended-spectrum beta-lactamase producing Enterobacteriaceae on the outcomes of transrectal needle biopsies of the prostate
شماره ركورد :
35198
Abstract :
Objective: This study aimed to address the prevalence, the risk factors and the results of fecal carriage of extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-PE) in patients who had undergone transrectal needle biopsy of the prostate (TRNBP). Patients and Methods: A total of 143 patients who had undergone TRNBP were included. Of these, 33(23%) had fecal carriage of ESBL-PE. The mean age of the patients was 62 ± 7.5 (43-81) years. Results: A univariate analysis showed that quinolone or other antibiotic use within the last 2 months, prostatitis, and diabetes mellitus (DM) were significantly associated with the presence of ESBL-PE. A multivariate analysis showed that quinolone use within the past 2 months (OR: 4.865; CI: 1.45-16.1), and DM (OR: 4.04; CI: 1.64-10) were found to be significant. Development of dysuria (p 0.001), fever (p=0.046) and chills (p=0.002) after TRNBP were shown to be related to the presence of ESBL-PE . There was no asymptomatic bacteriuria and sepsis, the rate of symptomatic urinary tract infection was 19%. Conclusion: This study showed that pre-biopsy risk factors for the presence of ESBL-PE were quinolone or other antibiotic use within the last 2 months and presence of DM. Changing prophylactic regimens should not be recommended due to the low rate of severe complications.
From Page :
127
NaturalLanguageKeyword :
Extended , spectrum beta , lactamases , Transrectal needle biopsy of the prostate , Fecal carriage , Infection
JournalTitle :
Marmara Medical Journal
To Page :
129
Link To Document :
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