Author/Authors :
Koçyiğit, İsmail Doruk Kırıkkale Üniversitesi - Diş Hekimliği Fakültesi - Ağız, Diş ve Çene Cerrahisi Anabilim Dalı, Türkiye , Tunalı, Mustafa GATA Haydarpaşa Eğitim Hastanesi - Diş Hekimliği, Periodontoloji Anabilim Dalı, Türkiye , Özdemir, Hakan Cumhuriyet Üniversitesi - Diş Hekimliği Fakültesi - Periodontoloji Anabilim Dalı, Türkiye , Kartal, Yasemin , Süer, Berkay Tolga GATA Haydarpaşa Eğitim Hastanesi - Diş Hekimliği, Ağız, Diş ve Çene Cerrahisi Anabilim Dalı, Türkiye
Abstract :
The therapeutic use of autologous platelet-rich fibrin constitutes a relatively new biotechnology that has been a breakthrough in the stimulation and acceleration of soft-tissue and bone healing. The efficiency of this process lies in the local and continuous delivery of a wide range of growth factors and proteins, mimicking the needs of the physiological wound healing and reparative tissue processes. Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates, with simplified processing and without biochemical blood handling. This easy protocol allows the production of leukocyte and platelet-rich fibrin clots starting from autologous blood samples. PRF is used especially in clinical Periodontal and Oral and Maxillofacial Surgery applications. The significance of the PRF is gradually increasing