Ozdilek, Betul Erenkoy Research and Education Hospital for Neurologic and Psychiatric Disorders - Department of Neurology, Turkey , Kenangil, Gulay Erenkoy Research and Education Hospital for Neurologic and Psychiatric Disorders - Department of Neurology, Turkey

The relationship between cognition and the non-cognitive clinical findings in Turkish patients with Parkinson’s disease

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The study intended to examine the relationship between cognition and the clinical features at the onset of Parkinson disease (PD) in Turkish patients. Fifty patients were included and their cognitive status was evaluated by using the Turkish version of the Montreal Cognitive Assessment (MoCA-TR) test. Clinical findings were obtained by using all of the subparts of the Unified Parkinson’s Disease Rating Scale (UPDRS). Disease severity was measured using the Hoehn and Yahr staging scale, and the Schwab-England Activities of Daily Living scale was used to assess the patients’ disability. Bivariate correlation analysis was conducted to examine the demographic factors, disease duration, presenting motor symptoms (tremor or bradykinesia) and laterality (right or left), and the unique contributions of the UPDRS subscores to cognitive dysfunction on the MoCATR. This study carried out among PD patients revealed that, 36% (18/50) had cognitive impairment (score of 21) on the MoCA-TR. Significant correlations were observed between cognitive impairment on the MoCA-TR and age, education level, subjective memory complaints, and the UPDRS I and II subscores and total score; whereas the age at disease onset, type of clinical presentation, and laterality of motor symptoms were notassociated with cognitive dysfunction.

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Clinical findings , Cognitive dysfunction , Montreal Cognitive Assessment , Parkinson’s disease

Journal Of Experimental an‎d Clinical Medicine

66