Author/Authors
OZGUNDUZ, Hediye Irem Yildiz Technical University - Chemical-Metallurgical Faculty - Chemical Engineering Department, Turkey , KANDILCI, Hava Gizem Yildiz Technical University - Chemical-Metallurgical Faculty - Chemical Engineering Department, Turkey , ACARALI, Nil Yildiz Technical University - Chemical-Metallurgical Faculty - Chemical Engineering Department, Turkey , SARAC, Hanifi Yildiz Technical University - Chemical-Metallurgical Faculty - Chemical Engineering Department, Turkey
Title Of Article
PRODUCTION AND OPTIMIZATION METHOD OF SMART HYDROGELS BASED ON BIOCOMPATIBLE POLYMER FOR CONTROLLED INSULIN RELEASE
شماره ركورد
41728
Abstract
The aim of controlled insulin delivery study experiments is to produce the smart hydrogel to use insulin release for human body. Insulin entrapped p(HEMA-co-Eudragit L-100) hydrogels containing different ratios of 2-Hydroxyethyl methacrylate (HEMA) and Eudragit L-100 were synthesized by using ammonium persulfate (APS) as an initiator and ethylene glycol dimethacrylate (EGDMA) as a cross linker and new alternative ways were worked on to find and develop. Taguchi method was used and optimum synthesis conditions were determined. Insulin was entrapped into hydrogels as synthesis. After entrapped method, loading efficiency values were calculated. and the hydrogels produced were characterized by using Fourier Transform Infrared Spectroscopy (FT-IR) and Scanning electron microscope (SEM) analysis.
From Page
115
NaturalLanguageKeyword
Hydrogel , insulin , Taguchi , Eudragit.
JournalTitle
Sigma Journal Of Engineering and Natural Sciences
To Page
122
JournalTitle
Sigma Journal Of Engineering and Natural Sciences
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