Author/Authors
başyiğit, esra anadolu university - faculty of pharmacy - department of pharmaceutical chemistry, Turkey , acar, ulviye anadolu university - faculty of pharmacy - department of pharmaceutical chemistry, Turkey , özkay, yusuf anadolu university - faculty of pharmacy - department of pharmaceutical chemistry, Turkey , karaca gençer, hülya anadolu university - faculty of pharmacy - department of pharmaceutical microbiology, Turkey , uçucu, ümit anadolu university - faculty of pharmacy - department of pharmaceutical chemistry, Turkey
Title Of Article
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NOVEL QUINOXALINE HYDRAZONES
شماره ركورد
41991
Abstract
A new class of 10 novel quinoxaline hydrazones was synthesized to examine their antimicrobial activity. The structures of the compounds were confirmed by IR, 1H-NMR, and MS spectral data and elemental analyses. Antimicrobial activity of the compounds was evaluated against 3 fungal and 7 bacterial strains by Micro-broth dilution assay. All of the synthesized compounds showed significant antibacterial activity against Pseudomonas aeruginosa. Furthermore, antibacterial activity of the 2,4- difluoro substituted compound 4b displayed two fold better activity than chloramphenicol against this bacterial strain.
From Page
31
NaturalLanguageKeyword
Quinoxaline , Hydrazone , Antimicrobial activity , Micro , broth dilution , Pseudomonas aeruginosa
JournalTitle
Anadolu University Journal of Science and Technology C - Life Sciences and Biotechnology
To Page
39
JournalTitle
Anadolu University Journal of Science and Technology C - Life Sciences and Biotechnology
Link To Document