Myocardial Performance Index in Patients with Coronary Slow Flow

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Objective: This study was aimed to investigate the left ventriculer myocardial performance index (Tei index) in patients with coronary slow flow phenomenon Material and Methods: 25 patients with slow coronary flow (15 men; 10 women; mean age 51 ± 12 years) and 20 subjects with angiographically normal coronary arteries (12 men; 8 women; mean age 52 ± 12 years) were included in the study. All the subjects underwent echocardiography and tissue Doppler imaging to determine left ventriculer (LV) diastolic functions and left ventriculer myocardial performance index (LV MPI). Results: Conventional echocardiography parameters, maximal velocity of early diastolic filling (p=0,02), ratio of maximal early to late diastolic filling (p=0,037) were significantly lower, deceleration time of early diastolic filling was significantly higher (p=0,043) in the patient group. Among tissue Doppler parameters the mitral annulus peak early diastolic velocity and ratio of early to late diastolic velocity were lower in patients group than in controls (p 0,001) but isovolumetric relaxation time were significantly increased in patients group than controls (p 0,001). LV MPI was significantly prolonged in coronary slow flow group ( p 0,001). TIMI frame count was negatively correlated with the mitral lateral annulus early diastolic velocity and the ratio of mitral lateral annulus early to late diastolic velocity whereas it was positively correlated with mitral isovolumetric relaxation time and LV MPI. Conclusion: Our findings demonstrate that patients with coronary slow flow phenomenon affects diastolic functions and LV MPI. Therefore, patients with coronary slow flow phenomenon should be carefully followed-up.

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Ventriculer function , coronary circulation , echocardiography

Kocatepe Medical Journal

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Kocatepe Medical Journal