Author/Authors
arduç, ayşe sağlık bakanlığı - ankara numune eğitim ve araştırma hastanesi, endokrinoloji ve metabolizma hastalıkları kliniği, Ankara, turkey , gökay, ferhat sağlık bakanlığı - ankara numune eğitim ve araştırma hastanesi, endokrinoloji ve metabolizma hastalıkları kliniği, Ankara, turkey , akbaba, gülhan sağlık bakanlığı - ankara numune eğitim ve araştırma hastanesi, endokrinoloji ve metabolizma hastalıkları kliniği, turkey , berker, dilek sağlık bakanlığı - ankara numune eğitim ve araştırma hastanesi, endokrinoloji ve metabolizma hastalıkları kliniği, turkey , güler, serdar hitit universitesi - tıp fakültesi, endokrinoloji ve metabolizma hastalıkları kliniği, turkey
Title Of Article
CUSHING’S SYNDROME PRESENTING WITH METASTATIC GIANT ADRENOCORTICAL CANCER: A CASE REPORT
شماره ركورد
42312
Abstract
Adrenocortical carcinoma is a rare tumor with poor prognosis. Cushing’s syndrome is the most common clinical presentation but adrenocortical carcinoma is one of the rare causes of Cushing’s syndrome. Because of the rarity, we report a patient who had cortisol-secreting metastatic giant adrenocortical carcinoma in the article. 46-year-old female with a history of malignant melanoma presented with weight gain, hirsutism, menstrual irregularities. She had abdominal obesity, hirsutism, and acneiform eruptions. Her midnight serum cortisol and 24-hour urinary cortisol were high; adrenocorticotropic hormone was low. 2mg and 8mg dexamethasone suppression tests were not suppressed. Adrenal magnetic resonance imaging showed 7x8x9cm right adrenal mass. The patient underwent adrenalectomy. Adrenocortical carcinoma was detected on pathological examination. Despite the chemotherapy (cisplatin+etoposide+mitotane) was given, she died 36 months later because of disseminated adrenocortical carcinoma.
From Page
38
NaturalLanguageKeyword
Adrenocortical carcinoma , malignant melanoma , cushing’s syndrome
JournalTitle
Kocatepe Medical Journal
To Page
41
JournalTitle
Kocatepe Medical Journal
Link To Document