Imaging of radionuclide emissions with a low-noise charge-coupled device

Author

Karellas, Andrew ; Liu, Hong ; Reinhardt, Christopher ; Harris, Lisa J. ; Brill, A.B.

Author_Institution

Massachusetts Univ., Med. Center, Worcester, MA, USA

Volume

40

Issue

4

fYear

1993

fDate

8/1/1993 12:00:00 AM

Firstpage

979

Lastpage

982

Abstract

The adaptation of a cooled charged-coupled device (CCD) for some autoradiographic applications which may alleviate some of the problems encountered with film is investigated. The proposed approach uses a scientific-grade CCD which is optically coupled via a lens to a scintillator without intermediate amplification. On the basis of experience with lens coupling, the performance of the CCD is investigated with the option of a fiberoptic coupling between the scintillator and CCD. The attainable performance by operating the CCD in the charge integration mode is explored experimentally, and computations are presented in order to predict the performance of a modified imaging system operating in the counting pulse-height mode for energy discrimination

Keywords

CCD image sensors; biomedical equipment; discriminators; pulse height analysers; radioisotope scanning and imaging; scintillation counters; CCD; autoradiographic applications; charge integration mode; cooled charged-coupled device; counting pulse-height mode; energy discrimination; fiberoptic coupling; film; lens coupling; low-noise charge-coupled device; modified imaging system; optically coupled; radionuclide emissions; scientific-grade; scintillator; Charge coupled devices; Charge-coupled image sensors; Dynamic range; Electrons; Lenses; Optical coupling; Optical films; Optical imaging; Optical sensors; Spatial resolution;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/23.256696

Filename

256696