Title :
The Goodman-Kruskal coefficient and its applications in genetic diagnosis of cancer
Author :
Jaroszewicz, Szymon ; Simovici, Dan A. ; Kuo, Winston P. ; Ohno-Machado, Lucila
Author_Institution :
Dept. of Comput. Sci., Univ. of Massachusetts, Boston, MA, USA
fDate :
7/1/2004 12:00:00 AM
Abstract :
Increasing interest in new pattern recognition methods has been motivated by bioinformatics research. The analysis of gene expression data originated from microarrays constitutes an important application area for classification algorithms and illustrates the need for identifying important predictors. We show that the Goodman-Kruskal coefficient can be used for constructing minimal classifiers for tabular data, and we give an algorithm that can construct such classifiers.
Keywords :
arrays; cancer; genetics; medical diagnostic computing; pattern classification; Goodman-Kruskal coefficient; bioinformatics; cancer; classification algorithms; gene expression; genetic diagnosis; microarrays; pattern recognition; predictors; Bioinformatics; Biological tissues; Cancer; Cells (biology); Computer science; DNA; Gene expression; Genetics; Glass; Pattern recognition; Algorithms; Cluster Analysis; Diagnosis, Computer-Assisted; Genetic Screening; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2004.827267