Title :
Structural Prediction of Dynamic Bayesian Network With Partial Prior Information
Author :
Maiti, Aniruddha ; Reddy, Ramakanth ; Mukherjee, Anirban
Author_Institution :
Dept. of Electr. Eng., Indian Inst. of Technol., Kharagpur, Kharagpur, India
Abstract :
The prediction of the structure of a hidden dynamic Bayesian network (DBN) from a noisy dataset is an important and challenging task. This work presents a generalized framework to infer the DBN network structure with partial prior information. In the proposed framework, the partial information about the network structure is provided in the form of prior. The proposed method makes use of the prior information regarding the presence and as well as absence of some of the edges. Using the noisy dataset and partial prior information, this method is able to infer nearly accurate structure of the network. The proposed method is validated using simulated datasets. In addition, two real biological datasets are used to infer hidden biological interaction networks.
Keywords :
Bayes methods; cancer; cellular biophysics; molecular biophysics; DBN structural prediction; biological interaction networks; dynamic Bayesian network; partial prior information; Approximation algorithms; Bayes methods; Biological system modeling; Data models; Nanobioscience; Noise measurement; Proteins; Cancer cell line; dynamic Bayesian Network; partial prior; structural learning;
Journal_Title :
NanoBioscience, IEEE Transactions on
DOI :
10.1109/TNB.2014.2361838