Title :
Ultrasound scattering from blood with hematocrits up to 100%
Author :
Mo, L.Y. ; Kuo, I.-Y. ; Shung, K.K. ; Ceresne, L. ; Cobbold, R.S.C.
Author_Institution :
GE Medical Syst., Milwaukee, WI, USA
Abstract :
The backscattering coefficient of saline suspensions of porcine red blood cells was measured for hematocrits up to about 90%. It was found that the coefficient peaks at approximately 15%, but then, contrary to what a simple "gap theory" might suggest, it decays smoothly to zero, without showing another peak at high hematocrits. A one-dimensional (1D) slab scattering model, in which the number of slabs per unit length represents the hematocrit and whose thickness and acoustical properties are similar to red cells/plasma, was also used to investigate the relation between the backscattered power and hematocrit. Monte-Carlo simulations performed for randomized boundary conditions show a similar relation to that of the 3D system. The experimental data is compared to the Percus-Yevick theory for the packing of hard spheres, and the simulated data is compared to the Percus-Yevick theory for infinite slabs.
Keywords :
Monte Carlo methods; bioacoustics; blood; cellular biophysics; physiological models; suspensions; ultrasonic scattering; 1D slab scattering model; Monte-Carlo simulations; Percus-Yevick theory; acoustical properties; backscattered power; blood ultrasound scattering; hard spheres packing; hematocrit; infinite slabs; plasma; porcine red blood cells; randomized boundary conditions; Acoustic scattering; Backscatter; Boundary conditions; Plasma properties; Plasma simulation; Red blood cells; Slabs; Suspensions; Ultrasonic imaging; Ultrasonic variables measurement; Animals; Computer Simulation; Erythrocytes; Hematocrit; Swine;
Journal_Title :
Biomedical Engineering, IEEE Transactions on