Title :
Automatic Brachytherapy Seed Placement Under MRI Guidance
Author :
Patriciu, Alexandru ; Petrisor, Doru ; Muntener, Michael ; Mazilu, Dumitru ; Schär, Michael ; Stoianovici, Dan
Author_Institution :
Johns Hopkins Univ. Sch. of Med., Baltimore
Abstract :
The paper presents a robotic method of performing low dose rate prostate brachytherapy under magnetic resonance imaging (MRI) guidance. The design and operation of a fully automated MR compatible seed injector is presented. This is used with the MrBot robot for transperineal percutaneous prostate access. A new image-registration marker and algorithms are also presented. The system is integrated and tested with a 3T MRI scanner. Tests compare three different registration methods, assess the precision of performing automated seed deployment, and use the seeds to assess the accuracy of needle targeting under image guidance. Under the ideal conditions of the in vitro experiments, results show outstanding image-guided needle and seed placement accuracy.
Keywords :
biological organs; biomedical MRI; brachytherapy; cancer; image registration; medical image processing; medical robotics; robot vision; MRI guidance; MrBot robot; automated seed deployment; image-guided needle; image-registration marker; low dose rate prostate brachytherapy; low magnetic resonance imaging guidance; registration methods; robotic method; seed placement accuracy; transperineal percutaneous prostate; Biomedical imaging; Brachytherapy; Diseases; Magnetic resonance imaging; Medical treatment; Needles; Prostate cancer; Radiology; Robotics and automation; Ultrasonic imaging; Brachytherapy; IGI; MR Compatible; image-guided robot; Algorithms; Brachytherapy; Humans; Image Interpretation, Computer-Assisted; Injections; Magnetic Resonance Imaging; Prosthesis Implantation; Robotics;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2007.900816