Title :
BioFET sensor for detection of albumin in urine
Author :
Park, K.M. ; Lee, S.-K. ; Sohn, Y.-S. ; Choi, S.Y.
Author_Institution :
Sch. of Electr. Eng. & Comput. Sci., Kyungpook Nat. Univ., Daegu
Abstract :
Characterisation of a BioFET for detection of albumin in a mixture of human urine is presented. To avoid electrolyte effect of the urine, it was measured in PBS (phosphate buffer saline) at a fixed pH after albumin binding. The drain current was modulated by the albumin bound to the anti-albumin immobilised on the gate surface of the BioFET. The current variation ratio was likely to be proportional to the concentration of the albumin in the range 50-250 mg/1. The results show the feasibility of the BioFET as a urinary albumin sensor.
Keywords :
biochemistry; biomedical measurement; biosensors; field effect transistors; molecular biophysics; patient diagnosis; proteins; BioFET sensor; albumin binding; albumin detection; albumin immobilization; drain current; urinary albumin sensor; urine;
Journal_Title :
Electronics Letters
DOI :
10.1049/el:20083551
