Title :
Normalisation of Histogrammed List Mode Data
Author :
Thielemans, Kris ; Morel, Christian ; Jacobson, Matthew W. ; Kaempf, Jerome H. ; Mustafovic, Sanida
Author_Institution :
Hammersmith Imanet Ltd., London
Abstract :
Many PET scanners nowadays have the possibility to record event-by-event information, known as list mode data. This has the advantage of keeping the data in the highest possible resolution (both temporal and spatial). In most cases, list mode data are then binned into sinogram format before reconstruction. In this paper, we discuss at which stage normalisation factors should be introduced. It is shown that noise is greatly reduced by performing the normalisation after the binning. We illustrate this with acquired and simulated data for the quad HiDAC camera.
Keywords :
image scanners; medical image processing; positron emission tomography; PET scanners; quad HiDAC camera; sinogram format; stage normalisation factors; Animals; Cameras; Detectors; Event detection; Jacobian matrices; Medical services; Noise reduction; Positron emission tomography; Spatial resolution; Statistical analysis; Data normalisation; PET; list mode;
Journal_Title :
Nuclear Science, IEEE Transactions on
DOI :
10.1109/TNS.2007.914207