Title :
Nanobiosensing Using Plasmonic Nanoprobes
Author_Institution :
Duke Univ., Durham
Abstract :
This paper provides an overview of the development and applications of plasmonics-active nanoprobes in biomedical diagnostics. Specific examples of detection techniques using surface-enhanced Raman scattering are presented to illustrate the usefulness and potential of the plasmonics nanoprobes for gene detection and nanobiosensing. The detection of specific target deoxyribonucleic acids sequences using a novel "molecular sentinel" nanoprobe method is presented and discussed in detail.
Keywords :
DNA; biosensors; genetics; molecular biophysics; nanobiotechnology; patient diagnosis; plasmonics; surface enhanced Raman scattering; biomedical diagnostics; gene detection; gene diagnostics; molecular sentinel; nanobiosensing; plasmonics-active nanoprobes; specific target deoxyribonucleic acid sequence; surface-enhanced Raman scattering; Dielectric substrates; Electromagnetic radiation; Electrons; Frequency; Nanobioscience; Nanostructures; Plasmons; Raman scattering; Rough surfaces; Surface roughness; Gene diagnostics; Raman; metallic nanostructures; nanoprobes; near-field detection; plasmonics; surface-enhanced Raman scattering (SERS);
Journal_Title :
Selected Topics in Quantum Electronics, IEEE Journal of
DOI :
10.1109/JSTQE.2007.914738
