DocumentCode
1070576
Title
A Metric on the Space of Reduced Phylogenetic Networks
Author
Nakhleh, Luay
Author_Institution
Dept. of Comput. Sci., Rice Univ., Houston, TX, USA
Volume
7
Issue
2
fYear
2010
Firstpage
218
Lastpage
222
Abstract
Phylogenetic networks are leaf-labeled, rooted, acyclic, and directed graphs that are used to model reticulate evolutionary histories. Several measures for quantifying the topological dissimilarity between two phylogenetic networks have been devised, each of which was proven to be a metric on certain restricted classes of phylogenetic networks. A biologically motivated class of phylogenetic networks, namely, reduced phylogenetic networks, was recently introduced. None of the existing measures is a metric on the space of reduced phylogenetic networks. In this paper, we provide a metric on the space of reduced phylogenetic networks that is computable in time polynomial in the size of the networks.
Keywords
bioinformatics; computational complexity; directed graphs; evolution (biological); genetics; trees (mathematics); acyclic graphs; directed graphs; leaf labeled graphs; phylogenetic networks; reduced phylogenetic network space metric; reticulate evolutionary histories; rooted graphs; time polynomial computable problem; Phylogeny; indistinguishability; metric.; phylogenetic network; reduced phylogenetic network; Algorithms; Computational Biology; Evolution; Models, Genetic; Phylogeny;
fLanguage
English
Journal_Title
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
Publisher
ieee
ISSN
1545-5963
Type
jour
DOI
10.1109/TCBB.2009.2
Filename
4752805
Link To Document