Title :
Decomposition of Magnetoencephalographic Data Into Components Corresponding to Deep and Superficial Sources
Author :
Zkurt, Tolga Esat Ö ; Sun, Mingui ; Sclabassi, Robert J.
Author_Institution :
Dept. of Electr. & Comput. Eng., Pittsburgh Univ., Pittsburgh, PA
fDate :
6/1/2008 12:00:00 AM
Abstract :
We extend the signal space separation (SSS) method to decompose multichannel magnetoencephalographic (MEG) data into regions of interest inside the head. It has been shown that the SSS method can transform MEG data into a signal component generated by neurobiological sources and a noise component generated by external sources outside the head. In this paper, we show that the signal component obtained by the SSS method can be further decomposed by a simple operation into signals originating from deep and superficial sources within the brain. This is achieved by using a scheme that exploits the beamspace methodology that relies on a linear transformation that maximizes the power of the source space of interest. The efficiency and accuracy of the algorithm are demonstrated by experiments utilizing both simulated and real MEG data.
Keywords :
biological techniques; biology computing; decomposition; magnetoencephalography; medical signal processing; neurophysiology; source separation; beamspace methodology; brain; decomposition; linear transformation; magnetoencephalographic data; neurobiological sources; noise component; signal space separation; superficial sources; Biosensors; Inverse problems; Magnetic heads; Magnetic sensors; Magnetic separation; Power harmonic filters; Sensor arrays; Signal generators; Signal processing algorithms; Space power stations; Sun; Beamspace; Biomagnetism; beamspace; biomagnetism; inverse problem; magnetoencephalography; magnetoencephalography (MEG); signal space separation; signal space separation (SSS); source localization; spatial filtering; spherical harmonics;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2008.919120