Title :
Optofluidic Intracavity Spectroscopy of Canine Lymphoma and Lymphocytes
Author :
Shao, Hua ; Wang, Weina ; Lana, S.E. ; Lear, Kevin L.
Author_Institution :
Colorado State Univ., Fort Collins
fDate :
4/1/2008 12:00:00 AM
Abstract :
Multiple transverse mode, intracavity spectra of canine lymphoma cells in a passive Fabry-Perot cavity are distinct from single-mode spectra of normal lymphocytes. Two-dimensional effective-index modal calculations provide insight into the nuclear size versus refractive index relationship and clarify the impact of lateral optical confinement on modal shift.
Keywords :
bio-optics; cancer; cellular biophysics; microfluidics; refractive index; spectroscopy; Fabry-Perot cavity; canine lymphocytes; canine lymphoma; effective-index modal calculations; optofluidic intracavity spectroscopy; refractive index; Biomedical optical imaging; Cells (biology); Mirrors; Optical interferometry; Optical refraction; Optical resonators; Optical scattering; Optical sensors; Optical variables control; Spectroscopy; Biophotonics; effective index model; optical cancer diagnostics; optofluidic intracavity spectroscopy;
Journal_Title :
Photonics Technology Letters, IEEE
DOI :
10.1109/LPT.2008.918252
