Comments, with reply, on "Point source nerve bundle stimulation: effects of fiber diameter and depth on simulated excitation" by K.W. Altman and R. Plonsey

Author

Solomonow, Moshe

Author_Institution

Dept. of Orthopaedic Surg. Louisiana State Univ., New Orleans, LA, USA

Volume

38

Issue

4

fYear

1991

fDate

4/1/1991 12:00:00 AM

Firstpage

390

Abstract

The commenter questions some assertions made in the above-mentioned work by K.W. Altman and R. Plansey (see ibid., vol.37, p.688-98, 1990), which describes a simulation study relating the electrical excitability of nerve axons to their diameter and depth in the bundle. The commenter also points out the lack of experimental validation of their simulation work as well as their ignoring the membrane capacitance and strength/duration relationship. In their reply, the authors make clear that in the paper they evaluated a strength/diameter relationship that describes a measure of the relative propensity for activation and they examined how this relationship changes as a function of depth within the nerve bundle.<>

Keywords

bioelectric phenomena; neurophysiology; electrical excitability; experimental validation; fiber depth; fiber diameter; membrane capacitance; nerve axons; nerve bundle; point source; simulated excitation; simulation work; strength/diameter relationship; strength/duration relationship; Biomedical engineering; Biomembranes; Capacitance; Electrodes; Frequency; Medical simulation; Nerve fibers; Solid modeling; Steady-state; Surgery; Action Potentials; Axons; Cell Membrane; Electric Conductivity; Electric Stimulation; Models, Biological;

fLanguage

English

Journal_Title

Biomedical Engineering, IEEE Transactions on

Publisher

ieee

ISSN

0018-9294

Type

jour

DOI

10.1109/10.133237

Filename

133237