Title :
A laser-Doppler system for measuring distributions of blood particles in narrow flow channels
Author :
Nijhof, Evert-Jan ; Uijttewaal, Wim S J ; Heethaar, Robert M.
Author_Institution :
Dept. of Med. & Physiol. Phys., Utrecht Univ., Netherlands
fDate :
6/1/1994 12:00:00 AM
Abstract :
A laser-Doppler velocimeter with microscopic probe volume has been developed in order to measure concentration distributions of particles in flowing suspensions containing, e.g., blood cells or microspheres. Experiments on flow through simple geometries were performed to demonstrate the applicability of the apparatus. Velocity profiles could be measured with an inaccuracy of about 2% and a spatial resolution of 15 μm, whereas concentration measurements yielded typical inaccuracies of 7%. The determination of absolute particle concentrations without additional calibration was demonstrated to be feasible too
Keywords :
Doppler effect; biomedical measurement; channel flow; flow measurement; haemodynamics; haemorheology; laser velocimetry; suspensions; blood cells; concentration distributions; concentration measurements; distributions of blood particles; flowing suspensions; laser-Doppler velocimeter; microscopic probe volume; microspheres; narrow flow channels; spatial resolution; velocity profiles; Blood; Cells (biology); Geometrical optics; Microscopy; Particle measurements; Probes; Spatial resolution; Suspensions; Velocity measurement; Volume measurement;
Journal_Title :
Instrumentation and Measurement, IEEE Transactions on
