A laser-Doppler system for measuring distributions of blood particles in narrow flow channels

Author

Nijhof, Evert-Jan ; Uijttewaal, Wim S J ; Heethaar, Robert M.

Author_Institution

Dept. of Med. & Physiol. Phys., Utrecht Univ., Netherlands

Volume

43

Issue

3

fYear

1994

fDate

6/1/1994 12:00:00 AM

Firstpage

430

Lastpage

435

Abstract

A laser-Doppler velocimeter with microscopic probe volume has been developed in order to measure concentration distributions of particles in flowing suspensions containing, e.g., blood cells or microspheres. Experiments on flow through simple geometries were performed to demonstrate the applicability of the apparatus. Velocity profiles could be measured with an inaccuracy of about 2% and a spatial resolution of 15 μm, whereas concentration measurements yielded typical inaccuracies of 7%. The determination of absolute particle concentrations without additional calibration was demonstrated to be feasible too

Keywords

Doppler effect; biomedical measurement; channel flow; flow measurement; haemodynamics; haemorheology; laser velocimetry; suspensions; blood cells; concentration distributions; concentration measurements; distributions of blood particles; flowing suspensions; laser-Doppler velocimeter; microscopic probe volume; microspheres; narrow flow channels; spatial resolution; velocity profiles; Blood; Cells (biology); Geometrical optics; Microscopy; Particle measurements; Probes; Spatial resolution; Suspensions; Velocity measurement; Volume measurement;

fLanguage

English

Journal_Title

Instrumentation and Measurement, IEEE Transactions on

Publisher

ieee

ISSN

0018-9456

Type

jour

DOI

10.1109/19.293463

Filename

293463