Title :
Development of an evanescent wave fiber optic biosensor
Author :
Anderson, George P. ; Golden, Joe P. ; Cao, Lynn K. ; Wijesuriya, Daya ; Shriver-Lake, Lisa C. ; Ligler, Frances S.
Author_Institution :
Center for Bio/Molecular Sci. & Eng., Naval Res. Lab., Washington, DC, USA
Abstract :
Biosensors are uniquely qualified to meet the need for rapid, inexpensive analytical procedures. The authors´ intent was to develop a simple, real-time immunoassay that could process multiple samples in a semi-automated manner, while maintaining maximum versatility to permit its application under various conditions. To achieve this goal, the authors have developed a biosensor which detects antibody-antigen binding within the evanescent wave of an optical biosensor.<>
Keywords :
biomedical equipment; biosensors; fibre optic sensors; antibody-antigen binding detection; evanescent wave fiber optic biosensor; medical instrumentation; multiple samples processing; rapid inexpensive analytical procedures; semiautomated technique; simple real-time immunoassay; Biosensors; Fluorescence; Immune system; Monitoring; Optical fiber testing; Optical fibers; Optical surface waves; Optical waveguides; Probes; Surface waves;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
