DocumentCode
11099
Title
Autonomous Unobtrusive Detection of Mild Cognitive Impairment in Older Adults
Author
Akl, Ahmad ; Taati, Babak ; Mihailidis, Alex
Author_Institution
Inst. of Biomater. & Biomed. Eng., Univ. of Toronto, Toronto, ON, Canada
Volume
62
Issue
5
fYear
2015
fDate
May-15
Firstpage
1383
Lastpage
1394
Abstract
The current diagnosis process of dementia is resulting in a high percentage of cases with delayed detection. To address this problem, in this paper, we explore the feasibility of autonomously detecting mild cognitive impairment (MCI) in the older adult population. We implement a signal processing approach equipped with a machine learning paradigm to process and analyze real-world data acquired using home-based unobtrusive sensing technologies. Using the sensor and clinical data pertaining to 97 subjects, acquired over an average period of three years, a number of measures associated with the subjects´ walking speed and general activity in the home were calculated. Different time spans of these measures were used to generate feature vectors to train and test two machine learning algorithms namely support vector machines and random forests. We were able to autonomously detect MCI in older adults with an area under the ROC curve of 0.97 and an area under the precision-recall curve of 0.93 using a time window of 24 weeks. This study is of great significance since it can potentially assist in the early detection of cognitive impairment in older adults.
Keywords
brain; cognition; diseases; geriatrics; learning (artificial intelligence); medical signal detection; medical signal processing; support vector machines; ROC curve; autonomous unobtrusive detection; dementia; feature vectors; home-based unobtrusive sensing technologies; machine learning algorithms; mild cognitive impairment; older adults; precision-recall curve; random forests; signal processing; support vector machines; Biomedical measurement; Dementia; Feature extraction; Legged locomotion; Monitoring; Sensors; Vectors; Home Activity; Home activity; Machine Learning; Mild Cognitive Impairment; Older Population; Signal Processing; Smart Systems; Unobtrusive Sensing Technologies; Walking Speed; machine learning; mild cognitive impairment (MCI); older population; signal processing; smart systems; unobtrusive sensing technologies; walking speed;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.2015.2389149
Filename
7005481
Link To Document