An in vitro tissue model for evaluating the effect of carboxyhemoglobin concentration on pulse oximetry

Author

Mendelson, Yitzhak ; Kent, Joel C.

Author_Institution

Dept. of Biomed. Eng., Worcester Polytech. Inst., MA, USA

Volume

36

Issue

6

fYear

1989

fDate

6/1/1989 12:00:00 AM

Firstpage

625

Lastpage

627

Abstract

An in vitro tissue model for specific application to noninvasive transmittance pulse oximetry is discussed. The model was used to assess the effect of variations in carboxyhemoglobin concentration on noninvasive measurements of arterial hemoglobin oxygen saturation. The model is also potentially useful for assessing the effect on the accuracy of noninvasive pulse oximeters of other physiological and physical variables, such as blood hemocrit, methemoglobin concentration, arterial blood pulsations, blood temperature, and variations in the peak emission wavelengths of the LEDs in the optical sensor.

Keywords

biomedical equipment; biomedical measurement; blood; LED peak emission wavelength; arterial blood pulsations; blood hemocrit; blood temperature; carboxyhaemoglobin concentration effect; in vitro tissue model; methemoglobin concentration; pulse oximetry; Biological system modeling; Biological tissues; Biomedical optical imaging; Blood; In vitro; In vivo; Infrared heating; Optical pulses; Predictive models; Pulse measurements; Carboxyhemoglobin; Humans; Models, Structural; Oximetry; Oxygen;

fLanguage

English

Journal_Title

Biomedical Engineering, IEEE Transactions on

Publisher

ieee

ISSN

0018-9294

Type

jour

DOI

10.1109/10.29457

Filename

29457