Title :
A multi-target tracking sensor platform for dielectrophoresis-based characterization of cells
Author :
Dickerson, Samuel J. ; Coraluppi, Stefano ; Carthel, Craig ; Levitan, Steven P. ; Chiarulli, Donald M.
Author_Institution :
Nanophoretics LLC, Monroeville, PA, USA
Abstract :
In this paper, we present a sensor platform for characterizing cells using dielectrophoresis. With our approach, we use a multi-target multiple-hypothesis tracking algorithm to automatically capture dielectrophoresis velocity information about the cells contained in a mixture. The algorithm we implemented is scalable and suitable for use with real-world samples where there is a high concentration of cells to characterize. We implement our method as a compact, low-power device that can be used in point-of-care applications and present results of the sensor platform characterizing yeast cells.
Keywords :
biochemistry; biological techniques; cellular biophysics; electrophoresis; dielectrophoresis based cell characterization; dielectrophoresis velocity information; multitarget tracking sensor platform; yeast cells; Dielectrophoresis; Electric fields; Electrodes; Force; Hardware; History; Target tracking;
Conference_Titel :
Healthcare Innovation Conference (HIC), 2014 IEEE
Conference_Location :
Seattle, WA
DOI :
10.1109/HIC.2014.7038893