Title :
Microcomputer-based interactive tracking of blood cells at biomaterial surfaces
Author :
Capson, David W. ; Maludzinski, Richard A. ; Feuerstein, Irwin A.
Author_Institution :
Dept. of Electr. & Comput. Eng., McMaster Univ., Hamilton, Ont., Canada
Abstract :
A microcomputer-based systems for analyzing the motion of human platelets and leukocytes at synthetic surfaces from a sequence of video frames on tape is described. The software is designed to provide convenient interaction with an operator to reduce the burden of manual analysis. In addition, the system computes and stores the cell movement data on disk for subsequent statistical analysis. Measurements include the number and nature of cell-to-surface collisions, residence times, and distances traveled.
Keywords :
biological techniques and instruments; biology computing; blood; cellular transport and dynamics; microcomputer applications; biomaterial surfaces; blood cells; cell-to-surface collisions; distance travelled; human platelets; leukocytes; microcomputer-based interactive tracking; residence time; statistical analysis; synthetic surfaces; video frames sequence; Animals; Biomedical engineering; Biomedical measurements; Blood; Cells (biology); Humans; Microscopy; Proteins; Protocols; Surface treatment; Biocompatible Materials; Blood Platelets; Cell Adhesion; Cell Movement; Humans; Microcomputers; Microscopy; Neutrophils; Platelet Adhesiveness; Rheology; Videotape Recording;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
