Microcomputer-based interactive tracking of blood cells at biomaterial surfaces

Author

Capson, David W. ; Maludzinski, Richard A. ; Feuerstein, Irwin A.

Author_Institution

Dept. of Electr. & Comput. Eng., McMaster Univ., Hamilton, Ont., Canada

Volume

36

Issue

8

fYear

1989

Firstpage

860

Lastpage

864

Abstract

A microcomputer-based systems for analyzing the motion of human platelets and leukocytes at synthetic surfaces from a sequence of video frames on tape is described. The software is designed to provide convenient interaction with an operator to reduce the burden of manual analysis. In addition, the system computes and stores the cell movement data on disk for subsequent statistical analysis. Measurements include the number and nature of cell-to-surface collisions, residence times, and distances traveled.

Keywords

biological techniques and instruments; biology computing; blood; cellular transport and dynamics; microcomputer applications; biomaterial surfaces; blood cells; cell-to-surface collisions; distance travelled; human platelets; leukocytes; microcomputer-based interactive tracking; residence time; statistical analysis; synthetic surfaces; video frames sequence; Animals; Biomedical engineering; Biomedical measurements; Blood; Cells (biology); Humans; Microscopy; Proteins; Protocols; Surface treatment; Biocompatible Materials; Blood Platelets; Cell Adhesion; Cell Movement; Humans; Microcomputers; Microscopy; Neutrophils; Platelet Adhesiveness; Rheology; Videotape Recording;

fLanguage

English

Journal_Title

Biomedical Engineering, IEEE Transactions on

Publisher

ieee

ISSN

0018-9294

Type

jour

DOI

10.1109/10.30814

Filename

30814