Adaptive sliding mode control for a general nonlinear multicompartment lung model with input pressure and rate saturation constraints

In this article, we develop an output feedback adaptive sliding mode controller for a general multicompartment lung mechanics model with nonlinear resistance and compliance respiratory parameters. Specifically, for a given clinically plausible reference volume pattern, we develop an adaptive sliding mode controller that accounts for input pressure and rate saturation constraints to automatically adjust the applied input so that the total lung volume tracks the given reference pattern. The proposed tracking control framework is applied to a two-compartment lung mechanics model with nonlinear lung compliance and resistance parameters.