DocumentCode :
1156912
Title :
High Spatial Resolution in \\beta -Imaging With a PIM Device
Author :
Donnard, Jerome ; Thers, Dominique ; Servagent, Noel ; Luquin, Lionel
Author_Institution :
SUBATECH Ecole des Mines de Nantes, Univ. de Nantes, Nantes
Volume :
56
Issue :
1
fYear :
2009
Firstpage :
197
Lastpage :
200
Abstract :
The autoradiography is an imaging technique able to locate in 2 dimensions molecules labeled with beta radioactive emitters. The usual technique in use is based on solid device, mostly films or phosphor screens. We report on tests performed with PIM (parallel ionization multiplier) on microscope slides demonstrating that MPGD (micro pattern gas detector) incorporating micromegas micro-meshes have to be considered for a next generation of beta-imager. The main advantages come from the high spatial resolution measured (25 mum FWHM in two dimensions) and from the event by event reconstruction position measurement resulting in ldquoon-linerdquo imaging availability in which no ldquoafter developmentrdquo have to be performed.
Keywords :
biomedical imaging; position measurement; radioisotope imaging; 2-dimension molecules; MPGD; PIM; autoradiography; beta radioactive emitters; beta-imaging; high spatial resolution; micropattern gas detector; microscope slides; parallel ionization multiplier; phosphor screens; position measurement; solid device; Gas detectors; High-resolution imaging; Ionization; Microscopy; Performance evaluation; Phosphors; Position measurement; Solids; Spatial resolution; Testing; Beta autoradiography; MPGD; PIM; beta rays; medical imaging;
fLanguage :
English
Journal_Title :
Nuclear Science, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9499
Type :
jour
DOI :
10.1109/TNS.2008.2005673
Filename :
4782145
Link To Document :
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