On Methods of Three-Dimensional Reconstruction from a Set of Radioisotope Scintigrams

The three-dimensional reconstruction of the radioisotope source distribution of coordinated radioisotope scintigrams is complicated by the point spreading function created by the imaging system (conical imaging) and the attenuation of gamma rays through the body. A new reconstruction method is proposed by converting the complicated existing reconstruction problem into the classical problem of weighted projection in the Fourier complex space upon which a modified additive algebraic reconstruction technique (ART) can be employed. Mathematical derivation, reconstruction algorithms, and illustrative computer results are included.