A model for controlling the resting membrane potential of cells using nanoparticles

This paper presents a novel dynamical system model for the resting membrane potential of cells. The novelty of this work is that the model allows parameters related to permeabilities of ion channels to be controlled so the resting membrane potential reaches a desired value. We are then able to explain the decreased polarity across the cell membrane when nanoparticles are introduced in the vicinity of a cell. The effect of varying these parameters on the resting membrane potential of a cell is investigated. The proposed model allows simulation of the behaviors of the resting membrane potential that matches experimental data.