Title :
Numerical FEM Models for the Planning of Magnetic Induction Hyperthermia Treatments With Nanoparticles
Author :
Candeo, A. ; Dughiero, F.
Author_Institution :
Dept. of Electr. Eng., Univ. of Padova, Padova
fDate :
3/1/2009 12:00:00 AM
Abstract :
A numerical FEM model of a magnetic fluid hyperthermia (MFH) treatment on an hepatocellular carcinoma (HCC) metastasis has been simulated. Starting from actual CT images of the patient, a 3-D geometry of the anatomical district has been reconstructed and a coupled electromagnetic and thermal transient analysis has been performed, in order to predict the temperature distribution during the treatment. The in vivo effect of blood perfusion has also been implemented through the Pennes´s model. Various simulations have been carried out, based on different particle sizes and concentrations, as well as different exciting field intensities.
Keywords :
blood; cancer; computerised tomography; diagnostic radiography; electromagnetic induction; finite element analysis; haemorheology; hyperthermia; image reconstruction; liver; magnetic fluids; magnetic particles; medical image processing; nanoparticles; particle size; patient treatment; physiological models; temperature distribution; tumours; 3-D geometry; CT images; Pennes´s model; blood perfusion; computed tomography; electromagnetic analysis; hepatocellular carcinoma metastasis; image reconstruction; in vivo effect; magnetic fluid; magnetic induction hyperthermia treatment planning; nanoparticles; numerical FEM model; particle concentration; particle size; temperature distribution prediction; thermal transient analysis; 3-D finite-element modeling (FEM); magnetic fluid hyperthermia (MFH); magnetic nanoparticles; treatment planning;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2009.2012769
