Numerical FEM Models for the Planning of Magnetic Induction Hyperthermia Treatments With Nanoparticles

Author

Candeo, A. ; Dughiero, F.

Author_Institution

Dept. of Electr. Eng., Univ. of Padova, Padova

Volume

45

Issue

3

fYear

2009

fDate

3/1/2009 12:00:00 AM

Firstpage

1658

Lastpage

1661

Abstract

A numerical FEM model of a magnetic fluid hyperthermia (MFH) treatment on an hepatocellular carcinoma (HCC) metastasis has been simulated. Starting from actual CT images of the patient, a 3-D geometry of the anatomical district has been reconstructed and a coupled electromagnetic and thermal transient analysis has been performed, in order to predict the temperature distribution during the treatment. The in vivo effect of blood perfusion has also been implemented through the Pennes´s model. Various simulations have been carried out, based on different particle sizes and concentrations, as well as different exciting field intensities.

Keywords

blood; cancer; computerised tomography; diagnostic radiography; electromagnetic induction; finite element analysis; haemorheology; hyperthermia; image reconstruction; liver; magnetic fluids; magnetic particles; medical image processing; nanoparticles; particle size; patient treatment; physiological models; temperature distribution; tumours; 3-D geometry; CT images; Pennes´s model; blood perfusion; computed tomography; electromagnetic analysis; hepatocellular carcinoma metastasis; image reconstruction; in vivo effect; magnetic fluid; magnetic induction hyperthermia treatment planning; nanoparticles; numerical FEM model; particle concentration; particle size; temperature distribution prediction; thermal transient analysis; 3-D finite-element modeling (FEM); magnetic fluid hyperthermia (MFH); magnetic nanoparticles; treatment planning;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2009.2012769

Filename

4787276