Information analysis for 3D SPECT imaging of radionuclide distributions in attenuating objects

Author

Wang, Huili ; Jaszczak, Ronald J. ; Coleman, R. Edward

Author_Institution

Dept. of Radiol., Duke Univ. Med. Center, Durham, NC, USA

Volume

41

Issue

4

fYear

1994

fDate

8/1/1994 12:00:00 AM

Firstpage

1612

Lastpage

1619

Abstract

The existing communication model of SPECT studies is extended by including the attenuating medium in the communication channel. Based on the extended model two fundamental theorems are presented to demonstrate the significance of the mutual information in system design and imaging reconstruction. In addition, the authors present a mutual information formula for SPECT systems to image radionuclide distributions in attenuating objects using single photon emission computed tomography (SPECT) collimators, The formula is, in turn, expressed in terms of the source distribution, attenuation coefficients, and collimator parameters such as collimator thickness, hole size, septal thickness, hole shape factor, and focal length. The polyhedral collimator is employed for the authors´ mutual information analysis in this report. Based on imaging surface decomposition, the analysis of the polyhedral collimator is reduced to the analysis of a single-headed collimator for planar imaging. Conventional collimators including parallel and cone beam collimators are used for the analysis of the single-headed collimator. The information loss due to attenuation is evaluated for myocardial imaging using technetium-99m and thalium-201

Keywords

computerised tomography; radioisotope scanning and imaging; 3D SPECT imaging; Tc; Tl; attenuating objects; attenuation coefficients; collimator parameters; collimator thickness; cone beam collimator; focal length; fundamental theorems; hole shape factor; hole size; information analysis; medical diagnostic imaging; nuclear medicine; parallel beam collimator; radionuclide distributions; septal thickness; single photon emission computerised tomography; single-headed collimator; source distribution; system design; technetium-99m; thalium-201; Attenuation; Communication channels; Image analysis; Image reconstruction; Information analysis; Mutual information; Optical collimators; Shape; Single photon emission computed tomography; System analysis and design;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/23.322957

Filename

322957