• DocumentCode
    1184967
  • Title

    A Small Analog Computer for Continuous Measurement of Intracellular Ion Activities

  • Author

    Berman, Pablo R. ; Brown, Arthur M.

  • Author_Institution
    Department of Physiology and Medicine, College of Medicine, University of Utah, Salt Lake City, Utah 84112.
  • Issue
    3
  • fYear
    1971
  • fDate
    5/1/1971 12:00:00 AM
  • Firstpage
    195
  • Lastpage
    200
  • Abstract
    The operation of liquid ion exchanger microelectrodes that allows measurement of internal potassium and chloride activities in identifiable neurons has been described. A computer that solves the logarithmic equation necessary for computation of these activities has been constructed and tested successfully. The great value of the computer is that it permits continuous measurement of these activities. When the internal ion activities change, such continuous measurement allows calculation of potassium and chloride permeabilities in single neurons.
  • Keywords
    Analog computers; Calibration; Electrodes; Equations; Kirchhoff´s Law; Microelectrodes; Neurons; Particle measurements; Permeability; Testing;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.1971.4502831
  • Filename
    4502831