Title :
Numerical simulations of light scattering by red blood cells
Author :
Karlsson, Anders ; He, Jiangping ; Swartling, Johannes ; Andersson-Engels, Stefan
Author_Institution :
Dept. of Electrosci., Lund Univ., Sweden
Abstract :
Scattering of electromagnetic waves from a red blood cell is simulated using the finite-difference time-domain method (FDTD), the Rytov approximation and the discrete dipole approximation (DDA). Both FDTD and DDA are full wave methods that give accurate results in a wide range of wavelengths. The Rytov approximation is a much simpler method that is limited to scattering angles within 30° from the forward direction. The investigation comprehends different wavelengths and different orientations of the cell. It shows that the shape, volume, and orientation of the cell have a large influence on the forward scattering.
Keywords :
bio-optics; blood; cellular biophysics; finite difference methods; light scattering; time-domain analysis; Rytov approximation; cell orientation; cell shape; cell volume; discrete dipole approximation; finite-difference time-domain method; light scattering; red blood cells; Biomedical optical imaging; Electromagnetic scattering; Finite difference methods; Light scattering; Numerical simulation; Optical refraction; Optical scattering; Red blood cells; Shape; Time domain analysis; Biological tissues; blood; optical propagation in nonhomogeneous media; optical scattering; Algorithms; Animals; Computer Simulation; Erythrocytes; Humans; Models, Cardiovascular; Numerical Analysis, Computer-Assisted; Photometry; Refractometry; Scattering, Radiation;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2004.839634
