Title :
A bivariate version of Andrews plots
Author :
Koziol, James A. ; Hacke, Werner
Author_Institution :
Dept. of Molecular & Exp. Med., Res. Inst. of Scripps Clinic, La Jolla, CA, USA
Abstract :
A bivariate version of Andrews plots for naturally paired multivariate date is introduced. The bivariate Andrews plots are space curves, and are particularly effective for revealing patterns and clusters when depicted dynamically. Projections of the bivariate Andrews plots recover the familiar univariate Andrews plots. As an example, a series of experiments conducted to characterize the neurologic and morphologic consequences of acute cerebral artery occlusion in an animal (baboon) model and to evaluate the ability of antithrombotic therapy to reverse cerebral ischemia following acute thrombotic stroke is described. Bivariate Andrews plots of the paired latencies and amplitudes were drawn. It is shown that the dynamic display of the space curves provides an immediate means of visualizing similarities and differences, without invoking formal statistical tests.
Keywords :
biophysics; Andrews plots; acute cerebral artery occlusion; acute thrombotic stroke; animal model; antithrombotic therapy; baboon; bivariate version; cerebral ischemia reversal; clusters; dynamic display; morphologic consequences; naturally paired multivariate date; neurologic consequences; patterns; space curves; statistical tests; Conductors; Covariance matrix; Data analysis; Fluid dynamics; Fourier series; Animals; Cerebrovascular Disorders; Electrophysiology; Mathematical Computing; Models, Neurological; Multivariate Analysis; Papio;
Journal_Title :
Biomedical Engineering, IEEE Transactions on