Title :
Improved beat-to-beat timing measurements of His-bundle signal
Author :
LeBlanc, A.Robert ; Mokrane, Abdelkader
Author_Institution :
Inst. de Genie Biomed., Montreal Univ., Que., Canada
Abstract :
A simplified bioelectric model of the atrioventricular (AV) junction is proposed to better understand the underlying biophysical generation of intracardiac His-bundle signal and to analyze the effects of electrocatheter displacements on waveform morphology and estimation of AV node conduction time (AVCT). Based on this model, an inverse problem approach has been developed to estimate electrode displacements occurring in real recordings. A measurement correction method is proposed to improve estimation of AVCT. Results illustrate autonomic influences on AVCT, a phenomenon hardly measured with common techniques.
Keywords :
biomedical measurement; electrocardiography; inverse problems; physiological models; timing; His-bundle signal; atrioventricular junction; autonomic influences; beat-to-beat timing measurements improvement; electrocatheter displacements effects; electrode displacements; intracardiac His-bundle signal; inverse problem approach; simplified bioelectric model; underlying biophysical generation; waveform morphology; Bioelectric phenomena; Displacement measurement; Heart; Inverse problems; Morphology; Signal analysis; Signal detection; Signal generators; Time measurement; Timing; Atrioventricular Node; Bundle of His; Electrodes; Electrophysiology; Heart Conduction System; Models, Cardiovascular; Myocardial Contraction; Signal Processing, Computer-Assisted;
Journal_Title :
Biomedical Engineering, IEEE Transactions on