• DocumentCode
    1214165
  • Title

    Automated Analysis of Rodent Three-Channel Electrocardiograms and Vectorcardiograms

  • Author

    Le, Hung T. ; Van Arsdel, William C. ; Makowski, Armand M. ; Pottala, Erik W. ; Bailey, James J.

  • Author_Institution
    IBM Corporation
  • Issue
    1
  • fYear
    1985
  • Firstpage
    43
  • Lastpage
    50
  • Abstract
    Exposure to toxic substances often produces alterations in heart rhythm and electrocardiographic waveform parameters such as PR interval, ST, etc. Analysis of such physiological changes is believed to provide sensitive indicators for revealing the degree of toxicity sustained. The purpose of this paper is to describe a system for automated analysis of electro-and vectorcardiograms in cardiotoxicity studies on rats. A selection of the best-suited methods of digital signal processing is also described.
  • Keywords
    Biology computing; Cardiology; Digital signal processing; Drugs; Electrocardiography; Humans; Laboratories; Pharmaceuticals; Rodents; Testing; Animals; Biomedical Engineering; Electrocardiography; Heart; Rats; Vectorcardiography;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.1985.325615
  • Filename
    4121923